Opiods(Smack, Afeem, Cough Syrup, Injections)
OPIOIDS
HAFFIM, DOODA , POSTA , SMACK , BROWN SUGAR, CODEINE, SPASMOPROXYVIN (DEXTROPROXYPHENE)
INJECTIONS
INJ FORTWIN (PENTAZOCINE), NORPHINE INJECTION, MORPHINE INJECTIONS
Table 4: Doses and duration of action of various opioids
|
Compound Dose (mg ) Oral Duration of Action |
|
Morphine 10 60 4 |
|
Heroin 4 30 3-4 |
|
Methadone 10 20 6-24 |
|
Pethidine 100 300 3 |
|
Codeine 30 90 4 |
|
Dextropropoxyphene — 200 8 |
|
Dihydrocodeine 15 45 4 |
|
Buprenorphine 60 180 3 |
|
Pentazocine 0.3 0.8 (sublingual) 7 |
Withdrawal
1.Yawning
2.Increased secretions from all opening of bodies nose, eyes, salivations, diarrhea and spontaneous erections
3.Pain in calf muscles
Treatment
Buprocare-n (buprenorphine and nalaxone ) 8 to 16 mg
Nalaxone for challenge test as it is dopamine antagonist short lasting only for few minute
Naltrexone for prophylaxis effective for three days but need to be given daily dosage 50mg daily for an year
Acute Opioid intoxication
A. The general criteria for acute intoxication (F1x.0) are met.
B. Dysfunctional behaviour as evidenced by at least one of the following:
(1) apathy and sedation;
(2) disinhibition;
(3) psychomotor retardation;
(4) impaired attention;
(5) impaired judgement;
(6) interference with personal functioning.
C. At least one of the following signs:
(1) drowsiness;
(2) slurred speech;
(3) pupillary constriction (except in anoxia from severe overdose when pupillary dilatation occurs)
(4) decreased level of consciousness (e.g. stupor, coma);
Comment : Acute Opioid intoxication when severe may be accompanied by respiratory depression (and hypoxia), hypotension and hypothermia.
Opioid withdrawal state
A. The general criteria for withdrawal state (F1x.3) are met. (Note that an opioid withdrawal state may also be induced by administration of an opioid antagonist after a brief period of opioid use.)
B. Any three of the following:
(1) craving for an opioid drug;
(2) rhinorrhoea or sneezing;
(3) lacrimation;
(4) muscle aches or cramps;
(5) abdominal cramps;
(6) nausea or vomiting;
(7) diarrhoea;
(8) pupillary dilatation;
(9) piloerection, or recurrent chills;
(10) tachycardia or hypertension;
(11) yawning;
(12) restless sleep.

